Research Articles
From Pixels to Patients: How 3D Game-Based Simulation is Revolutionizing Medical Education and Drug Development
This article explores the transformative role of 3D game-based simulation in medical education and professional training for researchers and drug developers.
2-Deoxyglucose (2-DG) Uptake and Metabolic Trapping: A Comprehensive Guide for Research and Therapeutic Development
This article provides a detailed, up-to-date analysis of the molecular mechanisms underlying 2-deoxyglucose (2-DG) cellular uptake and intracellular trapping.
![Validating 2-NBDG as a Non-Radioactive Alternative to [14C]2-DG: A Comprehensive Guide for Cellular Metabolism Research](https://raw.githubusercontent.com/chaoxiduerhong/D3F4C773DD50/refs/heads/main/all/cf69ec331298642f.jpg)
Validating 2-NBDG as a Non-Radioactive Alternative to [14C]2-DG: A Comprehensive Guide for Cellular Metabolism Research
This article provides a detailed analysis of the validation process for 2-NBDG, a fluorescent glucose analog, against the gold-standard radioactive 2-deoxyglucose ([14C]2-DG) uptake assay.
2-NBDG vs Click Chemistry Azide-Tagged Sugars: A Guide to Choosing Your Glucose Uptake Probe
This article provides a comprehensive guide for researchers on two dominant classes of probes for measuring cellular glucose uptake: the fluorescent glucose analog 2-NBDG and azide-tagged sugars for click chemistry...
2-NBDG vs. 6-NBDG: A Comparative Guide to Fluorescent Glucose Analogue Accuracy and Selection
This article provides a comprehensive, research-focused comparison of 2-NBDG and 6-NBDG, the two primary fluorescent glucose analogues used to monitor cellular glucose uptake.
Choosing the Right Glucose Assay: A Comprehensive Guide to 2-NBDG vs. ³H-2DG Validation and Applications
This comprehensive guide explores the critical validation and selection process between 2-NBDG and ³H-2DG glucose uptake assays.
When 2-NBDG Uptake Persists: Troubleshooting Glucose Transporter Blocker Failure in Research Assays
This article provides a comprehensive guide for researchers troubleshooting unexpected 2-NBDG uptake in the presence of classical glucose transporter (GLUT) inhibitors like cytochalasin B or phloretin.
Real-Time Glucose Uptake Monitoring with 2-NBDG: A Guide to Predicting Cancer Therapy Response in Cell Line Models
This comprehensive guide explores the 2-NBDG uptake assay as a powerful functional tool for monitoring therapy response in cancer cell lines.
Beyond the Fluorescent Signal: Critical Analysis of 2-NBDG Limitations and Non-Specific Binding in Cellular Glucose Uptake Assays
This article provides a comprehensive guide for researchers on the critical limitations of 2-NBDG, a widely used fluorescent glucose analog for measuring cellular glucose uptake.
Imaging Cellular Metabolism: A Complete 2-NBDG Fluorescence Protocol for Single-Cell Glucose Uptake Analysis
This comprehensive guide details the 2-NBDG fluorescence protocol for visualizing and quantifying glucose uptake at the single-cell level.